Histamine activates immune cells (basophils & mast cells) while causing blood vessels to dilate so that immune cells can be quickly transferred to kill pathogens
doi: 10.3389/fmicb.2024.1446595 Received 10 June 2024 Accepted 02 August 2024 Published 14 August 2024 Volume 15 - 2024 Edited by Daniela De Biase, Sapienza University of Rome, Italy Reviewed by Wolfgang Buckel, University of Marburg, Germany Malte Sinn, University of Konstanz, Germany Updates Copyright 2024 Piskol, Lukat, Kaufhold, Heger, Blankenfeldt, Jahn and Moser
10.1038/s41569-022-00735-4 56 FangY.ChenX.TanQ.ZhouH.XuJ.GuQ
95 Based on the clinical evidence available, magnesium appears to be of benefit for bone health in children and adolescents as well as in healthy adults and post-menopausal women at a dosage of 300 mg per day in children and 250750 mg per day in adults
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In addition, whatever the initial infectious agent, an inflamed, damaged gut mucosa allows microbial translocation, accompanied by the release of the bacterial and inflammatory endotoxin LPS
