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10.1111/nyas.14141 13 BrandK.SaarelainenL.SonajalgJ.BoutmyE.FochC.VaarasmakiM.et al (2022)

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Because of this potential effect on clot stabilization, individuals taking blood thinners may wish to avoid excessive use of sodium bicarbonate in baths, supplements, or antacids

Gently introduce the water, allowing it to run down the side of the vial, and then swirl gently until dissolved