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The FDA has issued repeated warnings about companies marketing unapproved peptides as research chemicals or selling them directly to consumers online (FDA warning on unapproved drugs)

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Lipolytic actions of leptin are dependent on the leptin receptor, since obese fa/fa Zucker rats (112) and db/db mice (32) that have an inactivating mutation of the long form of the leptin receptor are resistant to leptin-induced lipolysis

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