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7.1.1 High-throughput screening and multi-omics integration 7.1.1.1 Single-cell resolution technologies Single-cell transcriptomics (scRNA-seq) and chromatin accessibility sequencing (ATAC-seq) enable unprecedented cell-type-specific analysis of EED-induced epigenetic and transcriptional alterations (119)

The results showed that FA injection markedly enhanced the secretion of TNF- and IL-1 in the tubular epithelium, together with the increased infiltration of macrophage in the interstitial space, whereas LA supplementation downregulated the levels of these molecules

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In the diet, lignans often occur as complex precursors (like secoisolariciresinol diglucoside in flax) that are metabolized by gut microbiota into bioactive forms (54)