An emerging concept is that cardiolipin migration to the outer membrane of the mitochondrion is the trigger that induces misfolding into soluble oligomers of various proteins present in the cytoplasm
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Pentameric nCRP and CRP peptides 7782, 174185, and 201206 can control the inflammatory response resolving inflammation by reducing inflammatory cell endothelial adhesion and tissue migration, and the described CRP-mediated enhanced monocyte chemotaxis could be explained by local generation of mCRP (190, 191)
