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183,184 Finally, activation of the ALR/G protein-coupled high-affinity receptor in rats increases TNF- and IL-6 expression via the p38-MAPK pathway, thereby modulating the local immune microenvironment through macrophage activation and enhancing hepatic regeneration after PHx

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Evidence indicates that both ageing and chronic diseases such as metabolic syndrome, neurodegeneration and cancer are associated with alterations in the epigenome

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