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70 BCKDK inhibitors are also effective in attenuating insulin resistance in mouse models of obesity, and the development of a new generation of more powerful BCKDK inhibitors is important for diseases that require inhibition of BCAA catabolism

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Indication of the presence and speed at which LA reaches select sites within the porcine intestinal tract provides useful knowledge for developing future LA formulations to target other intestinal regions and to hasten/delay the release of LA at these sites and for other indications

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A decrease in red blood cell concentration (reflected in the hematocrit) will cause whole blood concentration to fall without a change in pharmacologically active concentrations