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Nicotine receptor stimulation promotes wake time and reduces both total sleep time and rapid eye movement sleep." [7] Effects of nicotine diagram [edit] Comparative risk assessment chart [edit] Addiction and dependence [edit] Psychological and physical dependence [edit] Nicotine, a key ingredient [35] in most e-liquids, [36] is well-recognized as one of the most addictive substances, as addictive as heroin and cocaine

However, other characteristics, such as size, shape or how the device functions may still allow it to imitate other products

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This only compares with the billions spent by tobacco companies on their marketing initiatives

L., Green, C

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