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10.1074/jbc.M507518200 J

There is evidence that chronic damage caused by oxidative stress may be involved in asthmatic inflammation and reduced lung function

Hematopoietic-derived macrophages originate from CD34+ hematopoietic stem cells (HSCs) in the bone marrow, progressing through granulocyte-monocyte progenitors and monocytic stages, before entering systemic circulation (3)