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The Dutch National Institute for Public Health and the Environment investigated heated tobacco products and writes in a summary on the website: The number of substances present in the air that is inhaled when using tobacco sticks with the iQOS is lower than in cigarette smoke, but that does not mean that the health risk of HTPs is equally lower

It has been reported that e-cigarettes may activate nicotinamide adenine dinucleotide phosphate oxidase and disrupt endothelial nitric oxide synthase (eNOS) activation and coupling, leading to a vicious cycle of superoxide generation, peroxynitrite formation, and tetrahydrobiopterin depletion, causing loss of nitric oxide (NO) and triggering vascular endothelial dysfunction 6

Another warning would have meant fines or worse

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In addition to the criminal charges, law enforcement authorities have seized more than 4,000 cartons of untaxed cigarettes, 22,000 untaxed cigars and nearly $400,000 in cash and property in the past three months