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Aged granulosa cells simultaneously accumulate DNA damage, detectable through markers such as H2AX and 53BP1, while DNA repair capacity (reflected by BRCA1, ATM, and checkpoint proteins TP53 and CDKN1A) becomes progressively compromised [186, 193,194,195,196,197,198,199]

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Activation of alpha-2 receptors inhibits adenylate cyclase, and lowers intracellular cAMP, which reduces aqueous humour production by the ciliary body

Alleviation of lead-induced physiological, metabolic, and ultramorphological changes in leaves of upland cotton through glutathione

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